Sequence Motifs, Consensus Sequences and The Motif Finding Problem
Sequence Motifs and their Biological Significance
Sequence motifs are nucleic acid sequences that are widespread across or within a genomes and have or are speculated to have certain regulatory or structural biological functions.
Motifs that are found in different parts of the genomes like exons, introns and junk, have different functions. Motifs present in the exons ( coding part of the genome) decide the structure of the protein or label proteins to be sent to certain parts of the cell for processes like phosphorylation. Motifs that are present in introns (which makes up the non coding part of genome) are usually the regulatory sequences which determine the amount of gene expression and binding sites of proteins. Satellite DNA, which is the main component of centromeres and heterochromatin, is an example of motif found in junk parts of the genome.
In this tutorial, we'll describe the mathematics behind Support Vector Machines. This tutorial is going to be much more math heavy as compared to other tutorials. If you're mostly interested in applying SVMs to solve problems, then our first tutorial on SVMs is sufficient. However, if you would like to understand the mathematical basis of Support Vector Machines, then you'll find this tutorial interesting.
In this tutorial, we will focus on the hard-margin SVM and soft-margin SVM. However, we will not be considering kernels or the hyper-parameter \gamma (gamma).
In SVM, the decision function for predicting data points x corresponds to the equation of an hyperplane:
Machine learning everywhere, why not in Competitive programming? – Anudeep's blog
[...] Let’s talk about some of the issues in CP platforms currently:
There is no recommendation system – Would it not be amazing if you get recommendations for similar problems based on what you have already solved?
Tags are mostly broken – They tell if a problem has math involved or binary search involved but does not give us any information about what in math or how complex it is. There are a lot of problems without tags.
It is very common for beginners to get struck on problems. Currently they search for an editorial or short explanations. Many problems do not have editorials or explanations (SPOJ, lots of regional contests, other coding camp problems, etc).
Also, in the case where an editorial exists, the programmer reads it and gets an idea of the whole solution. So that is a jump from 0 to 1. It would be better to give progressive hints on how to solve the problem, this wil...